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KMID : 0359719920100010079
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Journal of the Korean Neurological Association
1992 Volume.10 No. 1 p.79 ~ p.88
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Motor Evoked Potentials by Transcranial Magnetic Stimulation in Epileptic Patients
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Abstract
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This study was performed to verify whether transcranial magnetic stimulation (TMS) can induce seizures in epileptic patients or not and to compare motor evoked potentials (MEP) between patients with idiopathic epilepsy and normal control group.
MEP
were
elicited with TMS using a magnetie coil in 22 normal control group (16 men and 6 women) and 31 epileptic patients (19 men and 12 women). MEP were recorded by using digitimer magnetic stimulator model D190 and Medelec ER94a/Sensor apparatus, and
MEP
were
evoked by magnetic stmulations at the vertex, the 7th cervical vertebra and Erb's point. Central motor conduction time (CMCT) was calculated by su7btracting the latency of compound muscle action potentials from abductor p0ollicis brevis (APB)
muscle
obtained by magnetie stimulation over C7/T1 interspace form that obtained by stmulation over the motor cortex.
The mean latency, amplitude of MEP from APB nd CMCT at three stimulus sites. Were not significant difficant difference between age and height matched patients with generalized seizure and normal control group. in patients with focal seizure, the
mean
latency of MEP from APB and CMCT at three stmulus sites. Were not significant difference between involved site and uninvolved site.
Seizures of any type were not observed during and 1 hour after TMS in normal control group and epileptic patients. The seizure frequencies in 2 months before and after TMS were not significant difference in patients with focal seizure and
generalized
seizure.
This result suggested that TMS as currently used for the study of corticomotor evoked responses does not induce seizures in epileptic patients receiving antiepileptic drug therapy.
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KEYWORD
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